Group of Protein NMR spectroscopy | |
The main challenge of the "Protein NMR spectroscopy" Group is understanding the structural bases of life. Our general aim is to elucidate the physicochemical principles that determine the structure, dynamics, stability, folding and recognition of peptides, proteins, and nucleic acids, with a particular focus in disease-related biomolecules. This information is essential for a detailed description of their biological function. To that end, we use mainly high resolution multidimensional nuclear magnetic resonance (NMR) spectroscopy and get additional data from various biophysical techniques as well as from computational methods. Currently, our research lines are the following, contributing with the last two to facilitate and speed all others: | |
1. Structure, dynamics, stability and recognition in proteins and peptides of biomedical relevance 2. Intrinsically disordered proteins and phase transitions (monomer-to-condensate and monomer-to-amyloid) |